Dangers

Diagnosis can be a challenge because alien hand syndrome, according to the case reports in the medical literature, is truly a neurological disorder without a psychiatric component. This can be confusing during the diagnostic stage, particularly because true psychiatric disorders and behavioral issues are much more prevalent among patients than is alien hand syndrome, making complaints of a 'hand moving on its own,' far more likely to be accurately explained by something other than alien hand syndrome based on statistics alone. Therefore, careful observation and evaluation is required for the diagnosis of alien hand syndrome vs. any of the other condition in the differential diagnosis of these symptoms. 

There is also always the concern that the alien limb may do harmful acts to the persons' body, as many recorded cases have shown. People with this disease often live in fear of a person harming them and controlling their bodies.